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Get to know the research

The science behind the bears.

Magnesium, vitamin B6, and children’s attention: what studies have found.

In a larger study evaluating children with ADHD, 30 days of magnesium-vitamin B6 supplementation led to improved anxiety, attention, and hyperactivity. Magnesium treatment increased attention, work productivity, task performance, and decreased the proportion of errors. The EEG’s of children treated with magnesium showed positive changes as well, with brain waves significantly normalizing.

— James Greenblatt, MD, summarizing the research in Finally Focused: Mineral Imbalances & ADHD Part II ↗

Nutrition and attention: what we know

Magnesium and vitamin B6 have established nutritional roles in the nervous system. Researchers have also investigated their relationship with attention and behavior in children, including children with ADHD.

Some small studies report encouraging improvements after supplementation. However, study limitations and differences in participants, formulations, and doses make it difficult to predict who will benefit. The studies summarized here did not test Brainy Bears.

Magnesium levels in children with ADHD

A 2019 meta-analysis by Effatpanah and colleagues combined seven observational studies and found lower blood magnesium levels, on average, in people with ADHD compared with controls. Results varied substantially across studies.

Lower average levels do not mean that every child with ADHD is magnesium deficient. These studies cannot show that low magnesium causes ADHD, or that a child who struggles to sit still needs magnesium supplements.

What supplementation studies have found

Magnesium in children with identified deficiency: a 1997 study followed 50 children ages 7–12 with ADHD and magnesium deficiency who received magnesium for six months. Researchers reported reduced hyperactivity compared with 25 children receiving standard care without magnesium. The study was small and did not report a randomized, blinded placebo design.

Magnesium + B6: a 2006 study followed 40 children with ADHD symptoms receiving the combination for at least eight weeks. Researchers reported improvements in school attention, hyperactivity, and aggressiveness. It was an open study without a randomized placebo treatment group, so the supplement’s effect cannot be confidently separated from other influences.

These are early findings, not proof of an ADHD treatment. Study doses differed from the Brainy Bears serving; they should not be used as dosing instructions for your child.

Why magnesium citrate?

Magnesium helps maintain normal nerve and muscle function. Brainy Bears uses magnesium citrate. NIH identifies citrate as one of the forms generally absorbed more completely than magnesium oxide.

Absorption is one consideration when selecting an ingredient. It does not establish that a particular magnesium product improves attention or behavior.

Why vitamin B6?

Vitamin B6 helps the body make neurotransmitters, the chemical messengers used by nerve cells. Brainy Bears uses pyridoxine hydrochloride, a form of vitamin B6.

Researchers have studied magnesium and B6 together, but combined-ingredient studies cannot establish how much either ingredient contributed to an outcome. A nutrient’s normal role also does not prove that taking extra improves focus.

What this means for your family

Brainy Bears is a dietary supplement, not a treatment for ADHD or a replacement for prescribed care. Ingredient research is different from evidence about a finished product. We do not present these studies as clinical trials of Brainy Bears.

Follow your bottle’s directions and discuss supplement use with your child’s healthcare provider, especially if your child takes medication or other supplements. A clinician can help assess diet, possible deficiency, and attention concerns.

Further reading

References

  1. Greenblatt, J. (2019). Finally Focused: Mineral Imbalances & ADHD Part II. Psychiatry Redefined. ↗
  2. Effatpanah et al. (2019). Magnesium status and attention deficit hyperactivity disorder (ADHD): A meta-analysis. Psychiatry Research, 274, 228–234. ↗
  3. Starobrat-Hermelin & Kozielec (1997). The effects of magnesium physiological supplementation on hyperactivity in children with ADHD. Magnesium Research, 10(2), 149–156. ↗
  4. Mousain-Bosc et al. (2006). Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. I. Attention deficit hyperactivity disorders. Magnesium Research, 19(1), 46–52. ↗
  5. NIH Office of Dietary Supplements. Magnesium: Health Professional Fact Sheet. ↗
  6. NIH Office of Dietary Supplements. Vitamin B6: Health Professional Fact Sheet. ↗

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. As with any dietary supplement, consult your healthcare practitioner before using this product.